The key role of ergothioneine in label‐free surface‐enhanced Raman scattering spectra of biofluids: a retrospective re‐assessment of the literature
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14312
Abstract: Label‐free surface‐enhanced Raman scattering (SERS) has recently gained attention in the field of liquid biopsy as a rapid and relatively inexpensive technique that could significantly ease clinical diagnosis and prognosis by investigating a biofluid sample… read more here.
Keywords: label free; role; surface enhanced; ergothioneine ... See more keywords
Does Lactobacillus reuteri influence ergothioneine levels in the human body?
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14364
Abstract: The dietary thione‐thiol, ergothioneine (ET), accumulates in human and animal tissues and may play important roles in disease prevention. ET biosynthesis has only been described in fungi and certain bacteria, and humans and animals are… read more here.
Keywords: ergothioneine levels; influence ergothioneine; reuteri influence; ergothioneine ... See more keywords
Efficient Synthesis of Food-Derived Antioxidant l-Ergothioneine by Engineered Corynebacterium glutamicum.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c07541
Abstract: l-Ergothioneine (EGT) is a strong antioxidant used in industry, and it is commonly extracted from mushrooms; however, its production is limited. As an alternative, we developed metabolically engineered Corynebacterium glutamicum with reinforced sulfur assimilation and… read more here.
Keywords: corynebacterium glutamicum; egt; glutamicum; ergothioneine ... See more keywords
Distribution and accumulation of dietary ergothioneine and its metabolites in mouse tissues
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20021-z
Abstract: L-ergothioneine (ET) is a diet-derived amino acid that accumulates at high concentrations in animals and humans. Numerous studies have highlighted its antioxidant abilities in vitro, and possible cytoprotective capabilities in vivo. We investigated the uptake… read more here.
Keywords: ergothioneine; ergothioneine metabolites; distribution; dietary ergothioneine ... See more keywords
A novel antioxidant ergothioneine PET radioligand for in vivo imaging applications
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-97925-w
Abstract: Ergothioneine (ERGO) is a rare amino acid mostly found in fungi, including mushrooms, with recognized antioxidant activity to protect tissues from damage by reactive oxygen species (ROS) components. Prior to this publication, the biodistribution of… read more here.
Keywords: ergothioneine; 11c ergo; vivo; pet radioligand ... See more keywords
Quantitative determination of the sulfur-containing antioxidant ergothioneine by HPLC/ICP-QQQ-MS
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Analytical Atomic Spectrometry"
DOI: 10.1039/c7ja00030h
Abstract: Interest in the sulfur-containing antioxidant ergothioneine calls for reliable analytical methods for its quantification. In this work, a method based on reversed-phase high performance liquid chromatography (RP-HPLC) coupled with elemental mass spectrometry detection in mass… read more here.
Keywords: ergothioneine; determination; sulfur containing; containing antioxidant ... See more keywords
Ergothioneine Mitigates Telomere Shortening under Oxidative Stress Conditions.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of dietary supplements"
DOI: 10.1080/19390211.2020.1854919
Abstract: Shortened telomeres are associated with aging and age-related diseases. Oxidative stress is thought to be a major contributor to telomere shortening, and antioxidants may be able to mitigate these effects. Ergothioneine is a naturally occurring… read more here.
Keywords: ergothioneine; telomere shortening; stress conditions; telomere length ... See more keywords
Diet-Derived Antioxidants: The Special Case of Ergothioneine.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of food science and technology"
DOI: 10.1146/annurev-food-060822-122236
Abstract: This article reviews what is presently known about the biological roles of the diet-derived compound ergothioneine (ET). ET seems important to humans because it is rapidly taken up from the diet by a transporter largely… read more here.
Keywords: case ergothioneine; special case; antioxidants special; ergothioneine ... See more keywords
Validation of the Metabolite Ergothioneine as a Forensic Marker in Bloodstains
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27248885
Abstract: Ergothioneine, which is a naturally occurring metabolite, generally accumulates in tissues and cells subjected to oxidative stress, owing to its structural stability at physiological pH; therefore, it has been attracting attention in various biomedical fields.… read more here.
Keywords: validation metabolite; metabolite ergothioneine; marker; age ... See more keywords
Safe and Effective Antioxidant: The Biological Mechanism and Potential Pathways of Ergothioneine in the Skin
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28041648
Abstract: Ergothioneine, a sulfur-containing micromolecular histidine derivative, has attracted increasing attention from scholars since it was confirmed in the human body. In the human body, ergothioneine is transported and accumulated specifically through OCTN-1, especially in the… read more here.
Keywords: antioxidant biological; mechanism; safe effective; effective antioxidant ... See more keywords
Longitudinal Consumption of Ergothioneine Reduces Oxidative Stress and Amyloid Plaques and Restores Glucose Metabolism in the 5XFAD Mouse Model of Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15060742
Abstract: Background: Ergothioneine (ERGO) is a unique antioxidant and a rare amino acid available in fungi and various bacteria but not in higher plants or animals. Substantial research data indicate that ERGO is a physiological antioxidant… read more here.
Keywords: alzheimer disease; oxidative stress; 5xfad mice; glucose metabolism ... See more keywords