TSC2/Rheb signaling mediates ERK‐dependent regulation of mTORC1 activity in C2C12 myoblasts
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12195
Abstract: The enhanced rate of protein synthesis in skeletal muscle cells results in a net increase in total protein content that leads to skeletal muscle growth/hypertrophy. The mitogen‐activated protein kinase kinase (MEK)/extracellular signal‐regulated kinase (ERK)‐dependent regulation… read more here.
Keywords: c2c12 myoblasts; mtorc1; activation; erk dependent ... See more keywords
RNF144a induces ERK-dependent cell death under oxidative stress via downregulation of Vaccinia Related Kinase3.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cell science"
DOI: 10.1242/jcs.247304
Abstract: Vaccinia-related kinase 3 (VRK3) has been reported to be a negative regulator of ERK that protects cells from persistent ERK activation and inhibits ERK dependent apoptosis. Here we report that the E3 ligase, RNF144a, promotes… read more here.
Keywords: vrk3; rnf144a; erk dependent; vaccinia related ... See more keywords