β-hCG promotes epithelial ovarian cancer metastasis through ERK/MMP2 signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Cell Cycle"
DOI: 10.1080/15384101.2018.1558869
Abstract: ABSTRACT Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy, with typically extensive intraperitoneal implantation leading to poor prognosis. Our previous study preliminarily demonstrated β-hCG can promote tumorigenesis in immortalized nontumorigenic ovarian epithelial cells.… read more here.
Keywords: epithelial ovarian; mmp2 signaling; erk mmp2; metastasis ... See more keywords
DCLK1-Short Splice Variant Promotes Esophageal Squamous Cell Carcinoma Progression via the MAPK/ERK/MMP2 Pathway
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DOI: 10.1158/1541-7786.mcr-21-0161
Abstract: Cancer stem cell (CSC) marker doublecortin-like kinase 1 (DCLK1) contributes greatly to the malignancy of gastrointestinal cancers, and DCLK1-targeted agents have potential therapeutic value. However, the molecular pathways regulated by DCLK1-S (DCLK1 isoform 4), a… read more here.
Keywords: erk mmp2; progression; mapk erk; dclk1 ... See more keywords