ERK and c-Myc signaling in host-derived tumor endothelial cells is essential for solid tumor growth.
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2211927120
Abstract: The limited efficacy of the current antitumor microenvironment strategies is due in part to the poor understanding of the roles and relative contributions of the various tumor stromal cells to tumor development. Here, we describe… read more here.
Keywords: tumor growth; tumor stromal; endothelial cells; erk myc ... See more keywords
MicroRNA-144 targets APP to regulate AML1/ETO+ leukemia cell migration via the p-ERK/c-Myc/MMP-2 pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Oncology letters"
DOI: 10.3892/ol.2019.10477
Abstract: Extramedullary infiltration (EMI) is common in patients with acute myeloid leukemia (AML) and is closely associated with the prognosis of disease. We previously reported that patients carrying the AML1/ETO (A/E) fusion gene and expressing the… read more here.
Keywords: myc mmp; erk myc; myc; cell migration ... See more keywords