Terminalia chebula extracts ameliorate methamphetamine-induced memory deficits via activating the ERK and Nrf2 pathway
Sign Up to like & getrecommendations! Published in 2022 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2022.04.002
Abstract: As a psychoactive substance abused worldwide, methamphetamine (METH) abuse leads to multiple neurodegenerative symptoms including memory deficits. Terminalia chebula retzius extracts (TREs) isolated by our lab have great antioxidant activity and its effect on METH-induced… read more here.
Keywords: nrf2 pathway; memory; erk nrf2; induced memory ... See more keywords
Wogonin, a plant derived small molecule, exerts potent anti‐inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.02.041
Abstract: Abstract Osteoarthritis (OA), characterized by progressive destruction of articular cartilage, is the most common form of human arthritis. Here, we evaluated the potential chondroprotective and anti‐inflammatory effects of Wogonin, a naturally occurring flavonoid, in IL‐1&bgr;‐stimulated… read more here.
Keywords: wogonin; anti inflammatory; ros erk; expression ... See more keywords
Protection of 6-OHDA neurotoxicity by PGF2α through FP-ERK-Nrf2 signaling in SH-SY5Y cells.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology"
DOI: 10.1016/j.tox.2021.152686
Abstract: 6-Hydroxydopamine (6-OHDA) is a neurotoxin that destroy dopaminergic neurons and widely used to establish animal models of Parkinson's disease. Prostaglandins (PGs) are involved in various cellular processes, including the damage and repair of neuronal cells.… read more here.
Keywords: ohda induced; pgf2; nrf2 signaling; erk nrf2 ... See more keywords