Selenoprotein K Mediates the Proliferation, Migration, and Invasion of Human Choriocarcinoma Cells by Negatively Regulating Human Chorionic Gonadotropin Expression via ERK, p38 MAPK, and Akt Signaling Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Biological Trace Element Research"
DOI: 10.1007/s12011-017-1155-3
Abstract: Selenoprotein K (SelK), a member of selenoprotein family, is identified as a single endoplasmic reticulum (ER) transmembrane protein. Although over-expression of SelK inhibits adherence and migration of human gastric cancer BGC-823 cells, the effects of… read more here.
Keywords: p38 mapk; selk; human choriocarcinoma; erk p38 ... See more keywords
Lipopolysaccharide induced Interleukin‐6 production is mediated through activation of ERK 1/2, p38 MAPK, MEK, and NF&kgr;B in chicken thrombocytes
Sign Up to like & getrecommendations! Published in 2017 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.03.017
Abstract: &NA; Thrombocytes express Toll‐like receptor 4 and apparently use both mitogen‐activated protein kinase (MAPK) and nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NFKB) pathways for nuclear signaling. However, it is not well known if the… read more here.
Keywords: p38 mapk; production; kinase; erk p38 ... See more keywords
Oat β-glucan ameliorates epidermal barrier disruption by upregulating the expression of CaSR through dectin-1-mediated ERK and p38 signaling pathways.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.07.002
Abstract: The integrity of the epidermal barrier and the maintenance of barrier homeostasis depend on the dynamic balance between the proliferation and differentiation of keratinocytes. Calcium (Ca2+) plays a crucial role in maintaining a balance of… read more here.
Keywords: barrier; oat glucan; erk p38; epidermal barrier ... See more keywords
N-Acetyl-chitobiose ameliorates metabolism dysfunction through Erk/p38 MAPK and histone H3 phosphorylation in type 2 diabetes mice
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2016.11.012
Abstract: Abstract The effects of N-acetyl-chitobiose [(GlcNAc)2] on diabetes-related metabolic disorders, along with its regulation mechanism of mitogen-activated protein kinase (MAPK) signaling pathway were investigated on type 2 diabetes (T2D) model mice. Treatment with (GlcNAc)2 improved… read more here.
Keywords: erk p38; type diabetes; mapk; acetyl chitobiose ... See more keywords
ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2021.126758
Abstract: Organophosphorus compounds were proposed to impair immune surveillance and increase the total burden of pathogens. However, scarce attention has been paid to the effects of organophosphate flame retardants (OPFRs) on neutrophils. Previous literature outlined that… read more here.
Keywords: neutrophil extracellular; ros burst; formation; erk p38 ... See more keywords
Radix Paeoniae Rubra stimulates osteoclast differentiation by activation of the NF-κB and mitogen-activated protein kinase pathways
Sign Up to like & getrecommendations! Published in 2018 at "BMC Complementary and Alternative Medicine"
DOI: 10.1186/s12906-018-2196-7
Abstract: BackgroundRadix Paeoniae Rubra (RPR), a traditional Chinese herb, has anti-inflammatory and immuno-regulatory properties. This study explored the effects of RPR on stimulation of osteoclast differentiation in RAW264.7 cells and peripheral blood mononuclear cells (PBMC)s.MethodsThe mature… read more here.
Keywords: jnk erk; osteoclast differentiation; paeoniae rubra; erk p38 ... See more keywords
Deoxynivalenol Induces Inflammation in the Small Intestine of Weaned Rabbits by Activating Mitogen-Activated Protein Kinase Signaling
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2021.632599
Abstract: Deoxynivalenol (DON) can activate related signaling pathways and induce gastrointestinal disorders. Based on the results of previous studies, this study tried to explore the relationship between DON-induced intestinal inflammation of weaned rabbits and the ERK-p38… read more here.
Keywords: weaned rabbits; intestine; kinase; activated protein ... See more keywords
Antrodin C Isolated from Antrodia Cinnamomea Induced Apoptosis through ROS/AKT/ERK/P38 Signaling Pathway and Epigenetic Histone Acetylation of TNFα in Colorectal Cancer Cells
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12030764
Abstract: Background: Antrodin C, a maleimide derivative compound isolated from the ethanol extract of the mycelium of Antrodia cinnamomea, is an endemic fungus of Taiwan and a potential chemoprotective agent. However, the molecular mechanisms underlying the… read more here.
Keywords: cancer; akt erk; erk p38; ros akt ... See more keywords
Mechanisms for DNA-damaging agent-induced inactivation of ErbB2 and ErbB3 via the ERK and p38 signaling pathways.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology letters"
DOI: 10.3892/ol.2017.7532
Abstract: Cisplatin (CDDP) and doxorubicin (DOX) are chemotherapeutic drugs that trigger apoptosis by inducing DNA-damage. A previous study using breast cancer cells demonstrated the negative feedback modulation of the epidermal growth factor receptor (EGFR) and receptor… read more here.
Keywords: erk p38; erbb2; thr 677; erbb2 erbb3 ... See more keywords
Fibroblast growth factor 18 promotes proliferation and migration of H460 cells via the ERK and p38 signaling pathways.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology reports"
DOI: 10.3892/or.2016.5301
Abstract: Recently, fibroblast growth factor 18 (FGF18) expression was reported to be upregulated in colon cancer and ovarian cancer, and increased expression of FGF18 mRNA and protein is associated with tumor progression and poor overall survival… read more here.
Keywords: cell; erk p38; migration; growth ... See more keywords