Interaction of the Wnt/β-catenin and RAS-ERK pathways involving co-stabilization of both β-catenin and RAS plays important roles in the colorectal tumorigenesis.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in biological regulation"
DOI: 10.1016/j.jbior.2018.01.001
Abstract: Cancer development is usually driven by multiple genetic and molecular alterations rather than by a single defect. In the human colorectal cancer (CRC), series of mutations of genes are involved in the different stages of… read more here.
Keywords: catenin ras; tumorigenesis; catenin; erk pathways ... See more keywords
Lmod3 promotes myoblast differentiation and proliferation via the AKT and ERK pathways
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2020.112297
Abstract: Abstract Mutations in the Lmod3 gene have been identified as a genetic cause of nemaline myopathy. However, the mechanism underlying this disease and the function of Lmod3 remain largely unknown. In this study, we found… read more here.
Keywords: differentiation; myoblast differentiation; proliferation; erk pathways ... See more keywords