MicroRNA‐23a inhibits melanoma cell proliferation, migration, and invasion in mice through a negative feedback regulation of sdcbp and the MAPK/ERK signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.1979
Abstract: Melanoma is the main cause of death associated with skin cancer. Surgical resection and adjuvant therapy are currently effective treatments, but the recurrence rate is very high. The understanding of microRNA (miR) dynamics after surgical… read more here.
Keywords: sdcbp; sdcbp mapk; signaling pathway; erk signaling ... See more keywords
Rutin treats myocardial damage caused by pirarubicin via regulating miR‐22‐5p‐regulated RAP1/ERK signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22615
Abstract: Our experiments have previously demonstrated that rutin (RUT) can improve myocardial damage caused by pirarubicin (THP). However, the underlying molecular mechanisms remain uncertain. In this study, we developed an microRNA (miRNA) chip by replicating the… read more here.
Keywords: mir; myocardial damage; rap1 erk; signaling pathway ... See more keywords
MicroRNA‐374b inhibits cervical cancer cell proliferation and induces apoptosis through the p38/ERK signaling pathway by binding to JAM‐2
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26574
Abstract: Cervical cancer (CC) remains a highly prevalent cancer and mortality globally among women globally. The aim of the present study was to assess the ability of miR‐374b to regulate CC cells through JAM‐2, whilst exploring… read more here.
Keywords: mir 374b; jam; signaling pathway; p38 erk ... See more keywords
Inorganic arsenic promotes apoptosis of human immortal keratinocytes through the TGF‐β1/ERK signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23486
Abstract: Chronic exposure to high‐dose inorganic arsenic through groundwater, air, or food remains a major environmental public health issue worldwide. Apoptosis, a method of cell death, has recently become a hot topic of research in biology… read more here.
Keywords: erk signaling; tgf erk; apoptosis; signaling pathway ... See more keywords
Reconstructing ERK Signaling in the Drosophila Embryo from Fixed Images.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6424-6_25
Abstract: The early Drosophila embryo provides unique opportunities for quantitative studies of ERK signaling. This system is characterized by simple anatomy, the ease of obtaining large numbers of staged embryos, and the availability of powerful tools… read more here.
Keywords: drosophila embryo; erk activation; reconstructing erk; embryo ... See more keywords
Optogenetic Control of Ras/Erk Signaling Using the Phy-PIF System.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7154-1_1
Abstract: The Ras/Erk signaling pathway plays a central role in diverse cellular processes ranging from development to immune cell activation to neural plasticity to cancer. In recent years, this pathway has been widely studied using live-cell… read more here.
Keywords: system; ras erk; control ras; erk signaling ... See more keywords
β-arrestin2 mediates the hippocampal dopaminergic system in autistic mouse through the ERK signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2022.113888
Abstract: Autism is a complex neurodevelopmental disease that may be caused by genetic and environmental factors, that are incompletely understood. Overactivation of dopaminergic receptors can lead to autistic-like behavior. β-arrestin2 (Arrb2) is a scaffolding protein of… read more here.
Keywords: system; erk signaling; signaling pathway; like behavior ... See more keywords
Astragaloside IV inhibits progression of glioma via blocking MAPK/ERK signaling pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.07.052
Abstract: Glioma is one of the most common primary brain tumors in adults with a high mortality rate and relapse rate. Thus, finding better effective approaches to treat glioma has become very urgent. Astragaloside IV (AS-IV),… read more here.
Keywords: glioma; signaling pathway; erk signaling; astragaloside inhibits ... See more keywords
Benzophenone-3 induced abnormal development of enteric nervous system in zebrafish through MAPK/ERK signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.130670
Abstract: Hirschsprung disease (HSCR) is a congenital disease characterized by the absence of enteric neurons, which is derived from the failure of the proliferation, differentiation or migration of the enteric neural crest cells (ENCCs). HSCR is… read more here.
Keywords: mapk erk; development enteric; nervous system; enteric nervous ... See more keywords
Developmental ERK Signaling Goes Digital.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2017.08.023
Abstract: Reporting in Developmental Cell, de la Cova et al. (2017) present a biosensor to measure ERK activity dynamics in C. elegans larvae. They find that fate decision signaling involves frequency-modulated, digital ERK activity pulses. These findings may… read more here.
Keywords: signaling goes; goes digital; erk; developmental erk ... See more keywords
Effect of bFGF on the growth and matrix turnover of stem cells from human apical papilla: Role of MEK/ERK signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2019.12.013
Abstract: BACKGROUND/PURPOSE Basic fibroblast growth factor (bFGF) exhibits multiple biological functions in various tissues. Stem cells from apical papilla (SCAP) can be isolated from human apical papilla tissues in developmental teeth of children. The purposes of… read more here.
Keywords: mek erk; apical papilla; bfgf; scap ... See more keywords