Global Identification of ERK Substrates by Phosphoproteomics Based on IMAC and 2D-DIGE.
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DOI: 10.1007/978-1-4939-6424-6_10
Abstract: Extracellular signal-regulated kinase (ERK) regulates various cellular functions through phosphorylation of numerous downstream substrates, which have not yet been fully characterized. To date, several phosphoproteomic approaches have been employed to identify novel substrates for ERK.… read more here.
Keywords: erk substrates; dige; erk; global identification ... See more keywords
High-Throughput In Vitro Identification of Direct MAPK/Erk Substrates.
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DOI: 10.1007/978-1-4939-6424-6_9
Abstract: Phosphorylation mediated by cellular protein kinases is an effective mechanism employed by an organism to regulate central processes such as cell-cycle progression, metabolic pathways, cytoskeletal function, cell migration and differentiation. Thus, for example, various signaling… read more here.
Keywords: erk substrates; mapk erk; mapk; high throughput ... See more keywords