Independent and cooperative roles of the Mek/ERK1/2‐MAPK and PI3K/Akt/mTOR pathways during developmental myelination and in adulthood
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DOI: 10.1002/glia.23602
Abstract: Multiple extracellular and intracellular signals regulate the functions of oligodendrocytes as they progress through the complex process of developmental myelination and then maintain a functionally intact myelin sheath throughout adult life, preserving the integrity of… read more here.
Keywords: mek erk1; myelination; pi3k akt; developmental myelination ... See more keywords
Mek/ERK1/2‐MAPK and PI3K/Akt/mTOR signaling plays both independent and cooperative roles in Schwann cell differentiation, myelination and dysmyelination
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DOI: 10.1002/glia.24049
Abstract: Multiple signals are involved in the regulation of developmental myelination by Schwann cells and in the maintenance of a normal myelin homeostasis throughout adult life, preserving the integrity of the axons in the PNS. Recent… read more here.
Keywords: erk1 mapk; mek erk1; mtor; myelination ... See more keywords
The serine protease CORIN promotes progression of gastric cancer by mediating the ERK1/2 MAPK pathway
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DOI: 10.1002/mc.23739
Abstract: The serine protease CORIN catalyzes pro‐atrial natriuretic peptide (pro‐ANP) into an active ANP and maintains homeostasis of the internal environment. However, it is unclear whether CORIN participates in the regulation of tumor progression. We analyzed… read more here.
Keywords: erk1 mapk; progression; corin; serine protease ... See more keywords