Independent and cooperative roles of the Mek/ERK1/2‐MAPK and PI3K/Akt/mTOR pathways during developmental myelination and in adulthood
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23602
Abstract: Multiple extracellular and intracellular signals regulate the functions of oligodendrocytes as they progress through the complex process of developmental myelination and then maintain a functionally intact myelin sheath throughout adult life, preserving the integrity of… read more here.
Keywords: mek erk1; myelination; pi3k akt; developmental myelination ... See more keywords
Mek/ERK1/2‐MAPK and PI3K/Akt/mTOR signaling plays both independent and cooperative roles in Schwann cell differentiation, myelination and dysmyelination
Sign Up to like & getrecommendations! Published in 2021 at "Glia"
DOI: 10.1002/glia.24049
Abstract: Multiple signals are involved in the regulation of developmental myelination by Schwann cells and in the maintenance of a normal myelin homeostasis throughout adult life, preserving the integrity of the axons in the PNS. Recent… read more here.
Keywords: erk1 mapk; mek erk1; mtor; myelination ... See more keywords