Erlotinib-Gold(I) Complex Induces Leukemia Cell DC Differentiation and Remodels the Immunosuppressive Microenvironment.
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DOI: 10.1021/acs.jmedchem.4c01354
Abstract: Inducing differentiation of leukemia cells into dendritic cells (DC) is pivotal to reshaping the immunosuppressive microenvironment. Here, we report the synthesis of EG2, an erlotinib-gold(I) complex, which directly prompts the differentiation of acute myeloid leukemia… read more here.
Keywords: differentiation; immunosuppressive microenvironment; gold complex; erlotinib gold ... See more keywords