The disulfide isomerase ERp72 supports arterial thrombosis in mice.
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DOI: 10.1182/blood-2016-12-755587
Abstract: Several CGHC motif-containing disulfide isomerases support thrombosis. We here report that endoplasmic reticulum protein 72 (ERp72), with 3 CGHC redox-active sites (ao, a, and a'), supports thrombosis. We generated a new conditional knockout mouse model… read more here.
Keywords: erp72; aggregation; mice; platelet ... See more keywords