ErpY-like Lipoprotein of Leptospira Outsmarts Host Complement Regulation by Acquiring Complement Regulators, Activating Alternative Pathways, and Intervening in the Membrane Attack Complex.
Sign Up to like & getrecommendations! Published in 2022 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.1c00602
Abstract: The survival of pathogenic Leptospira in the host depends on its proficiency to circumvent the immune response. These pathogens evade the complement system in serum by enticing and amassing the serum complement regulators onto their… read more here.
Keywords: erpy like; complement; complement regulators; rerpy like ... See more keywords
Detection of anti-leptospiral antibodies using recombinant ErpY-Like lipoprotein based latex agglutination test for serodiagnosis of animal leptospirosis.
Sign Up to like & getrecommendations! Published in 2024 at "Letters in applied microbiology"
DOI: 10.1093/lambio/ovae100
Abstract: Precise and timely diagnosis is essential to prevent severe outcomes of leptospirosis in humans and animals. Existing diagnostic methods face challenges and limitations, underscoring the need for novel, field-applicable screening and diagnostic tests/assays. This study… read more here.
Keywords: recombinant erpy; agglutination; leptospirosis; agglutination test ... See more keywords