Correcting errors in PCR-derived libraries for rare allele detection by reconstructing parental and daughter strand information
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DOI: 10.1038/s42003-025-08537-3
Abstract: Molecular barcoding methods enable high-sensitivity detection of circulating tumor DNA that is rarely present in liquid biopsy samples. Many methods involve ligation of molecular barcodes to DNA prior to hybridization capture, enabling recovery of starting… read more here.
Keywords: detection; pcr derived; errors pcr; correcting errors ... See more keywords