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Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-04132-9
Abstract: Subsets of endogenous retroviruses (ERVs) are derepressed in mouse embryonic stem cells (mESCs) deficient for Setdb1, which catalyzes histone H3 lysine 9 trimethylation (H3K9me3). Most of those ERVs, including IAPs, remain silent if Setdb1 is…
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Keywords:
setdb1;
silencing somatic;
erv silencing;
somatic role ... See more keywords