Oridonin enhances γ‑globin expression in erythroid precursors from patients with β‑thalassemia via activation of p38 MAPK signaling.
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DOI: 10.3892/mmr.2019.10848
Abstract: Upregulation of fetal hemoglobin expression can alleviate the severity of β‑thalassaemia. This study aimed to investigate the effects of Oridonin (ORI, a diterpenoid compound) on γ‑globin expression in human erythroid precursor cells and the potential… read more here.
Keywords: p38 mapk; globin expression; expression; erythroid precursor ... See more keywords