Pathogenic Effects of M. tuberculosis-Specific Proteins ESAT-6 and CFP-10 in Macrophage Culture and in 3D-Granulemogenesis Model In Vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Bulletin of experimental biology and medicine"
DOI: 10.1007/s10517-021-05288-z
Abstract: We studied the effects of M. tuberculosis secretory proteins ESAT-6 and CFP-10 on the properties of vaccinal mycobacteria BCG not producing these proteins. Phagocytosis of M. bovis by macrophages, proliferation of mycobacteria in macrophages, apoptosis… read more here.
Keywords: proteins esat; esat cfp; effects tuberculosis; macrophage ... See more keywords
In Vitro and In Vivo Antigen Presentation and Diagnosis Development of Recombinant Overlapping Peptides Corresponding to Mtb ESAT-6/CFP-10
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DOI: 10.3389/fimmu.2022.872676
Abstract: Cellular immunity in Mycobacteria tuberculosis (Mtb) infection is important for the pathogenesis and final clearance of intracellular Mtb infection. In addition, it is valuable for the diagnosis of tuberculosis. In this pioneering work, we tested… read more here.
Keywords: rop; vitro vivo; esat cfp; mtb ... See more keywords
Study of CD27, CD38, HLA-DR and Ki-67 immune profiles for the characterization of active tuberculosis, latent infection and end of treatment
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DOI: 10.3389/fmicb.2022.885312
Abstract: Background Current blood-based diagnostic tools for TB are insufficient to properly characterize the distinct stages of TB, from the latent infection (LTBI) to its active form (aTB); nor can they assess treatment efficacy. Several immune… read more here.
Keywords: esat cfp; hla; cd38 hla; cd27 cd38 ... See more keywords