Backfilling cohorts in phase I dose-escalation studies.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical trials"
DOI: 10.1177/17407745231160092
Abstract: Background: The use of ‘backfilling’, assigning additional patients to doses deemed safe, in phase I dose-escalation studies has been used in practice to collect additional information on the safety profile, pharmacokinetics and activity of a… read more here.
Keywords: escalation studies; dose escalation; phase; phase dose ... See more keywords