Mathematical modeling of hypoxia and adenosine to explore tumor escape mechanisms in DC-based immunotherapy
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DOI: 10.1038/s41598-024-62209-6
Abstract: Identifying and controlling tumor escape mechanisms is crucial for improving cancer treatment effectiveness. Experimental studies reveal tumor hypoxia and adenosine as significant contributors to such mechanisms. Hypoxia exacerbates adenosine levels in the tumor microenvironment. Combining… read more here.
Keywords: hypoxia adenosine; tumor escape; adenosine; tumor ... See more keywords
Understanding of Immune Escape Mechanisms and Advances in Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/8901326
Abstract: Tumor immune escape has emerged as the most significant barrier to cancer therapy. A thorough understanding of tumor immune escape therapy mechanisms is critical for further improving clinical treatment strategies. Currently, research indicates that combining… read more here.
Keywords: cancer; tumor immune; escape mechanisms; tumor ... See more keywords
New Prognostic Gene Signature and Immune Escape Mechanisms of Bladder Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.775417
Abstract: Background: The immune microenvironment profoundly affects tumor prognosis and therapy. The present study aimed to reveal potential immune escape mechanisms and construct a novel prognostic signature via systematic bioinformatic analysis of the bladder cancer (BLCA)… read more here.
Keywords: signature; bladder cancer; immune escape; escape ... See more keywords
Endometrial Cancer Immune Escape Mechanisms: Let Us Learn From the Fetal–Maternal Interface
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DOI: 10.3389/fonc.2020.00156
Abstract: The immune escape mechanisms at the base of tumor progression in endometrial cancer mimic immune tolerance mechanisms occurring at the maternal–fetal interface. The biological and immunological processes behind the maternal–fetal interface are finely tuned in… read more here.
Keywords: escape mechanisms; immune escape; endometrial cancer; cancer ... See more keywords
Targets of Immune Escape Mechanisms in Cancer: Basis for Development and Evolution of Cancer Immune Checkpoint Inhibitors
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DOI: 10.3390/biology12020218
Abstract: Simple Summary The tumor immune escape mechanisms are key factors in cancer progression and metastasis. They are an undeniable hurdle for successful cancer treatment in patients. It has been widely recognized that cancer cells can… read more here.
Keywords: checkpoint inhibitors; immune checkpoint; immune escape; escape mechanisms ... See more keywords
The Immune Escape Mechanisms of Mycobacterium Tuberculosis
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DOI: 10.3390/ijms20020340
Abstract: Epidemiological data from the Center of Disease Control (CDC) and the World Health Organization (WHO) statistics in 2017 show that 10.0 million people around the world became sick with tuberculosis. Mycobacterium tuberculosis (MTB) is an… read more here.
Keywords: escape mechanisms; immune escape; tuberculosis; mechanisms mycobacterium ... See more keywords
Innate and adaptive immune escape mechanisms of hepatitis B virus
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v28.i9.881
Abstract: Chronic hepatitis B virus (HBV) infection is an international health problem with extremely high mortality and morbidity rates. Although current clinical chronic hepatitis B (CHB) treatment strategies can partly inhibit and eliminate HBV, viral breakthrough… read more here.
Keywords: immune; immune escape; hepatitis virus; innate adaptive ... See more keywords