Articles with "escaping cutoff" as a keyword



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Escaping from the Cutoff Paradox by Accumulating Long-Chain Alcohols in the Cell Membrane.

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Published in 2022 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.2c00629

Abstract: The mechanism for the cutoff, an activity cliff at which long-chain alcohols lose their biological effects, has not been elucidated. Highly hydrophobic oleyl alcohol (C18:1) exists as a mixture of monomers and aggregated droplets in… read more here.

Keywords: long chain; chain alcohols; escaping cutoff; membrane ... See more keywords