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   Articles with "escc" as a keyword



Long noncoding RNA SNHG12 induces proliferation, migration, epithelial–mesenchymal transition, and stemness of esophageal squamous cell carcinoma cells via post‐transcriptional regulation of BMI1 and CTNNB1

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recommendations! Published in 2020 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12683

Abstract: Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors around the world. Numerous studies have revealed the function of long noncoding RNAs (lncRNAs) in cancers, including ESCC. In this study, lncRNA… read more here.

Keywords: snhg12; cell; escc; proliferation migration ... See more keywords

Characterization of super‐enhancer‐associated functional lncRNAs acting as ceRNAs in ESCC

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recommendations! Published in 2020 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12726

Abstract: Long noncoding RNAs (lncRNAs) have important regulatory roles in cancer biology. Although some lncRNAs have well‐characterized functions, the vast majority of this class of molecules remains functionally uncharacterized. To systematically pinpoint functional lncRNAs, a computational… read more here.

Keywords: characterization super; lncrnas acting; acting cernas; escc ... See more keywords

Circular RNA circ-TNRC6B inhibits the proliferation and invasion of esophageal squamous cell carcinoma cells by regulating the miR-452-5p/DAG1 axis.

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recommendations! Published in 2023 at "Molecular oncology"

DOI: 10.1002/1878-0261.13432

Abstract: Previous studies have uncovered the key role of circular RNAs (circRNAs) in various diseases, including cancer. However, the growth-inhibitory effects of circRNAs on esophageal squamous cell carcinoma (ESCC) have not been completely elucidated. This study… read more here.

Keywords: escc; circ tnrc6b; dag1; mir 452 ... See more keywords

The TDP‐43/TP63 Positive Feedback Circuit Promotes Esophageal Squamous Cell Carcinoma Progression

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202402913

Abstract: Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent malignancies with a 5‐year survival rate of only 15% in patients with advanced diseases. Tumor protein 63 (TP63), a master transcription factor (TF) in… read more here.

Keywords: esophageal squamous; tp63; cell carcinoma; squamous cell ... See more keywords

A novel serum microRNA signature to screen esophageal squamous cell carcinoma

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recommendations! Published in 2017 at "Cancer Medicine"

DOI: 10.1002/cam4.973

Abstract: Circulating microRNAs (miRNAs) have been used as promising diagnostic biomarkers for esophageal squamous cell carcinoma (ESCC). We performed miRNA expression profiling using quantitative reverse transcription polymerase chain reaction (qRT‐PCR) based Exiqon panels from three ESCC… read more here.

Keywords: mir; squamous cell; serum; escc ... See more keywords

PIK3CB promotes oesophageal cancer proliferation through the PI3K/AKT/mTOR signalling axis

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recommendations! Published in 2022 at "Cell Biology International"

DOI: 10.1002/cbin.11847

Abstract: PIK3CB is abnormally expressed in various carcinomas and affects the proliferation, invasion and drug resistance of cancer cells. However, its role in oesophageal squamous cell carcinoma (ESCC) is still unclear. In this study, PIK3CB was… read more here.

Keywords: mtor signalling; pi3k akt; escc; pik3cb ... See more keywords
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TIM‐3 polymorphism is involved in the progression of esophageal squamous cell carcinoma by regulating gene expression

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recommendations! Published in 2021 at "Environmental and Molecular Mutagenesis"

DOI: 10.1002/em.22432

Abstract: The T‐cell immunoglobulin and mucin domain containing molecule 3 (TIM‐3), a crucial immune regulatory molecule, is an emerging immune checkpoint target for cancer therapy. Our study aimed to investigate the association between TIM‐3 polymorphisms (rs10053538… read more here.

Keywords: squamous cell; escc; expression; tim ... See more keywords

CXCR4 up‐regulation mediated by USP1 deubiquitination promotes the tumorigenesis and immune escape in esophageal squamous‐cell carcinoma

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recommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.70004

Abstract: CXC chemokine receptor 4 (CXCR4) and ubiquitin specific protease 1 (USP1) have been reported to involve in the tumorigenesis of esophageal squamous‐cell carcinoma (ESCC). Here, we investigated whether USP1 induced CXCR4 deubiquitination in regulating ESCC… read more here.

Keywords: deubiquitination; cxcr4; immune escape; cell ... See more keywords

Homeobox D10, a tumor suppressor, inhibits the proliferation and migration of esophageal squamous cell carcinoma

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recommendations! Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28644

Abstract: Esophageal squamous cell carcinoma (ESCC) is one of the most common types of esophageal cancer, which is the sixth leading cause of cancer death globally. Homeobox D10 (HOXD10) is a member of the homeobox (HOX)… read more here.

Keywords: proliferation migration; cell; escc; hoxd10 ... See more keywords
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Silencing of UAP1L1 inhibits proliferation and induces apoptosis in esophageal squamous cell carcinoma

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recommendations! Published in 2021 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.23278

Abstract: Esophageal squamous cell carcinoma (ESCC) is recognized as one of the malignant tumors with poor prognosis. UAP1L1 (UDP‐N‐acetylglucosamine‐1‐like‐1) affects numerous biological processes, which is a key regulator of the development of malignant tumors. The biological… read more here.

Keywords: squamous cell; cell carcinoma; esophageal squamous; escc ... See more keywords

Feed‐forward activation of STAT3 signaling limits the efficacy of c‐Met inhibitors in esophageal squamous cell carcinoma (ESCC) treatment

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recommendations! Published in 2021 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.23306

Abstract: c‐Hepatocyte growth factor receptor (Met) inhibitors have demonstrated clinical benefits in some types of solid tumors. However, the efficacy of c‐Met inhibitors in esophageal squamous cell carcinoma (ESCC) remains unclear. In this study, we discovered… read more here.

Keywords: efficacy met; met inhibitors; stat3; escc ... See more keywords