Esculetin alleviates murine lupus nephritis by inhibiting complement activation and enhancing Nrf2 signaling pathway.
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DOI: 10.1016/j.jep.2022.115004
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Esculetin is a bioactive compound of medicinal herb Hydrangea paniculata, and has showed anti-oxidation and anti-inflammation bioactivities. Renal local oxidative stress and inflammation are import contributors for progression of lupus nephritis (LN). AIM… read more here.
Keywords: esculetin could; lupus nephritis; pathway; complement activation ... See more keywords