LC-ESI-MS/MS method for the enantioseparation of six flavanones
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DOI: 10.1039/c6ay02952c
Abstract: An LC-ESI-MS/MS method enabling the enantioseparation of six flavanones (flavanone, naringenin, hesperetin, eriodictyol, liquiritigenin and pinostrobin) was developed and validated. Separation occurred in gradient mode on a Chiralpak AD-3R column. Detection was performed in positive… read more here.
Keywords: six flavanones; method enantioseparation; esi method; enantioseparation six ... See more keywords
Development and validation of an UPLC-ESI-MS/MS method for quantification of duvelisib in plasma: application to pharmacokinetic study in rats
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DOI: 10.1039/d3ra00310h
Abstract: Duvelisib (DUV) is a new oral phosphoinositide-3-kinase (PI3K)-δ and PI3K-γ inhibitor. It is used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). This study describes the development… read more here.
Keywords: development validation; esi method; plasma; method ... See more keywords
Simple and high sample throughput LC/ESI-MS/MS method for bioequivalence study of prazosin, a drug with risk of orthostatic hypotension
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DOI: 10.1080/03639045.2022.2125985
Abstract: Abstract Objective The study aimed to develop a rapid, simple and sensitive LC/ESI-MS/MS method to measure prazosin concentration in human plasma and apply bedside sampling in bioequivalence study of two prazosin tablets to resolve the… read more here.
Keywords: orthostatic hypotension; esi method; bioequivalence; method ... See more keywords
Application of LC-ESI-MS/MS Method for Analysis of Escitalopram Oxalate in Human Urine and Pharmaceutical Dosage Forms.
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DOI: 10.1093/chromsci/bmz073
Abstract: An effective and sensitive liquid chromatographic-electrospray ionization tandem mass-spectrometric (LC-ESI-MS/MS) method was developed and validated for quantification of escitalopram oxalate (ESC-OX), antidepressant drug in spiked human urine and pharmaceutical formulations. In this work, simple liquid-liquid… read more here.
Keywords: human urine; urine pharmaceutical; escitalopram oxalate; esi method ... See more keywords
Fast and Sensitive HPLC-ESI-MS/MS Method for Etoricoxib Quantification in Human Plasma and Application to Bioequivalence Study
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27175706
Abstract: Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. The objective of the current study was to develop a sensitive, fast and high-throughput HPLC-ESI-MS/MS method to measure etoricoxib levels in human… read more here.
Keywords: esi method; human plasma; hplc esi; method ... See more keywords