Neutrophils, eosinophils and intraepithelial lymphocytes in the squamous esophagus in subjects with and without gastroesophageal reflux symptoms.
Sign Up to like & getrecommendations! Published in 2021 at "Human pathology"
DOI: 10.1016/j.humpath.2021.06.004
Abstract: BACKGROUND Whilst intraepithelial lymphocytes (IELs) are considered normal within the distal esophageal mucosa, there is an appreciation of the potential role of excess lymphocytic infiltration in the pathogenesis of mucosal damage in reflux esophagitis. Furthermore,… read more here.
Keywords: intraepithelial lymphocytes; reflux; esophageal mucosa; upper limit ... See more keywords
Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41147-8
Abstract: There is an increasing prevalence of esophageal diseases but intact human tissue platforms to study esophageal function, disease mechanisms, and the interactions between cell types in situ are lacking. To address this, we utilized full… read more here.
Keywords: eosinophilic esophagitis; mucosa; esophageal mucosa; human esophageal ... See more keywords