ESR1 methylation in primary tumors and paired circulating tumor DNA of patients with high-grade serous ovarian cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2018.05.026
Abstract: OBJECTIVE Estrogen receptor, coded by the ESR1 gene, is highly expressed in epithelial ovarian cancer. ESR1 gene is frequently methylated in many types of gynecological malignancies. However, only a few studies attempted to investigate the… read more here.
Keywords: primary tumors; methylation; esr1 methylation; ovarian cancer ... See more keywords
ESR1 Methylation Measured in Cell-Free DNA to Evaluate Endocrine Resistance in Metastatic Breast Cancer Patients
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23105631
Abstract: ESR1 methylation was proposed as mechanism for endocrine resistance in metastatic breast cancer patients. To evaluate its potential as a minimally invasive biomarker, we investigated the feasibility of measuring ESR1 methylation in cell-free DNA (cfDNA)… read more here.
Keywords: methylation; resistance metastatic; esr1 methylation; endocrine resistance ... See more keywords