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Published in 2018 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2018.05.026
Abstract: OBJECTIVE Estrogen receptor, coded by the ESR1 gene, is highly expressed in epithelial ovarian cancer. ESR1 gene is frequently methylated in many types of gynecological malignancies. However, only a few studies attempted to investigate the…
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Keywords:
primary tumors;
methylation;
esr1 methylation;
ovarian cancer ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23105631
Abstract: ESR1 methylation was proposed as mechanism for endocrine resistance in metastatic breast cancer patients. To evaluate its potential as a minimally invasive biomarker, we investigated the feasibility of measuring ESR1 methylation in cell-free DNA (cfDNA)…
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Keywords:
methylation;
resistance metastatic;
esr1 methylation;
endocrine resistance ... See more keywords