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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0868-5_5
Abstract: An essential gene is defined as a gene that cannot be completely removed from the genome. Investigation of an essential gene function is limited because its deletion strain cannot be readily created. Here we describe…
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Keywords:
plasmid shuffling;
study essential;
essential gene;
gene ... See more keywords
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Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.1c00661
Abstract: Building multicellular microbial consortia that communicate with each other and perform programmed functionalities is the next milestone for synthetic biology. Achieving cell–cell communication within these communities requires programming of the transduction of an extracellular signal…
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Keywords:
cell;
essential gene;
growth;
gpcr activated ... See more keywords
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Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00323
Abstract: Carbon-neutral production of valuable bioproducts is critical to sustainable development but remains limited by the slow engineering of photosynthetic organisms. Improving existing synthetic biology tools to engineer model organisms to fix carbon dioxide is one…
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Keywords:
essential gene;
deletion;
conditionally essential;
gene ... See more keywords
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Published in 2017 at "Nature Reviews Genetics"
DOI: 10.1038/nrg.2017.141
Abstract: been to characterize genes that are essential for cellular or organismal viability. Such sets of genes — which are deemed the most important for survival — have numerous applications, including to design and engineer streamlined…
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Keywords:
gene essentiality;
essential genes;
drug;
essential gene ... See more keywords
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Published in 2021 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1009656
Abstract: Extra-chromosomal genetic elements are important drivers of evolutionary transformations and ecological adaptations in prokaryotes with their evolutionary success often depending on their ‘utility’ to the host. Examples are plasmids encoding antibiotic resistance genes, which are…
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Keywords:
essential gene;
gene;
plasmid inheritance;
acquisition ... See more keywords
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1
Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1154120
Abstract: Introduction: Essential genes are essential for the survival of various species. These genes are a family linked to critical cellular activities for species survival. These genes are coded for proteins that regulate central metabolism, gene…
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Keywords:
gene;
essential gene;
essential genes;
gene classification ... See more keywords
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Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.02331
Abstract: Genes critical for the survival or reproduction of an organism in certain circumstances are classified as essential genes. Essential genes play a significant role in deciphering the survival mechanism of life. They may be greatly…
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Keywords:
essential genes;
predict bacterial;
essential gene;
gene ... See more keywords