The Use of Tn-Seq and the FiTnEss Analysis to Define the Core Essential Genome of Pseudomonas aeruginosa.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1720-5_10
Abstract: Transposon-insertion sequencing (Tn-Seq) allows for identification of bacterial genes and pathways essential for growth under a given condition. A transposon mutant is created by the stable and random integration of a transposable element into a… read more here.
Keywords: pseudomonas aeruginosa; core essential; define core; essential genome ... See more keywords
DTYMK is essential for genome integrity and neuronal survival
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neuropathologica"
DOI: 10.1007/s00401-021-02394-0
Abstract: Nucleotide metabolism is a complex pathway regulating crucial cellular processes such as nucleic acid synthesis, DNA repair and proliferation. This study shows that impairment of the biosynthesis of one of the building blocks of DNA,… read more here.
Keywords: neuronal survival; essential genome; genome integrity; genome ... See more keywords
Comparative analysis of the Burkholderia cenocepacia K56-2 essential genome reveals cell envelope functions that are uniquely required for survival in species of the genus Burkholderia
Sign Up to like & getrecommendations! Published in 2017 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000140
Abstract: Burkholderia cenocepacia K56-2 belongs to the Burkholderia cepacia complex, a group of Gram-negative opportunistic pathogens that have large and dynamic genomes. In this work, we identified the essential genome of B. cenocepacia K56-2 using high-density… read more here.
Keywords: essential genome; cenocepacia; cenocepacia k56; burkholderia cenocepacia ... See more keywords