Prestin's fast motor kinetics is essential for mammalian cochlear amplification.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2217891120
Abstract: Prestin (SLC26A5)-mediated voltage-driven elongations and contractions of sensory outer hair cells within the organ of Corti are essential for mammalian cochlear amplification. However, whether this electromotile activity directly contributes on a cycle-by-cycle basis is currently… read more here.
Keywords: motor kinetics; cochlear amplification; essential mammalian; mammalian cochlear ... See more keywords
Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria
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DOI: 10.1093/nar/gkx1231
Abstract: Abstract Accuracy of protein synthesis is enabled by the selection of amino acids for tRNA charging by aminoacyl-tRNA synthetases (ARSs), and further enhanced by the proofreading functions of some of these enzymes for eliminating tRNAs… read more here.
Keywords: mammalian mitochondria; mischarged trnas; editing activity; essential mammalian ... See more keywords
Filamin C is Essential for mammalian myocardial integrity
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DOI: 10.1371/journal.pgen.1010630
Abstract: FLNC, encoding filamin C, is one of the most mutated genes in dilated and hypertrophic cardiomyopathy. However, the precise role of filamin C in mammalian heart remains unclear. In this study, we demonstrated Flnc global… read more here.
Keywords: mammalian heart; essential mammalian; heart; mammalian myocardial ... See more keywords