Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages
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DOI: 10.1038/s41467-021-21617-2
Abstract: Mitochondria are important regulators of macrophage polarisation. Here, we show that arginase-2 (Arg2) is a microRNA-155 (miR-155) and interleukin-10 (IL-10) regulated protein localized at the mitochondria in inflammatory macrophages, and is critical for IL-10-induced modulation… read more here.
Keywords: inflammatory macrophages; reprogramming inflammatory; essential metabolic; metabolic reprogramming ... See more keywords