BRD9 is an essential regulator of glycolysis that creates an epigenetic vulnerability in colon adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4954
Abstract: The intensive interplay between aberrant epigenetic events and metabolic remodeling represents one of the hallmarks of tumors, including colon cancer. The functions of Bromodomain Containing Protein BRD‐9 in colon cancer remains indefinite. We aimed to… read more here.
Keywords: essential regulator; brd9 essential; regulator glycolysis; colon cancer ... See more keywords
Etv2 as an essential regulator of mesodermal lineage development.
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DOI: 10.1093/cvr/cvx133
Abstract: The 'master regulatory factors' that position at the top of the genetic hierarchy of lineage determination have been a focus of intense interest, and have been investigated in various systems. Etv2/Etsrp71/ER71 is such a factor… read more here.
Keywords: lineage; essential regulator; biology; regulator mesodermal ... See more keywords
Transcriptional coregulator RIP140: an essential regulator of physiology.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-16-0156
Abstract: Transcriptional coregulators drive gene regulatory decisions in the transcriptional space. Although transcription factors including all nuclear receptors provide a docking platform for coregulators to bind, these proteins bring enzymatic capabilities to the gene regulatory sites.… read more here.
Keywords: coregulator rip140; rip140 essential; transcriptional coregulator; essential regulator ... See more keywords