Conditional deletion of mTOR discloses its essential role in early B‐cell development
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23386
Abstract: Mechanistic target of rapamycin (mTOR) is a serine‐threonine kinase and central regulator of cell growth, differentiation, and survival. mTOR is commonly hyperactivated in a diverse number of cancers and critical roles for mTOR in regulating… read more here.
Keywords: early cell; cell development; cell; essential role ... See more keywords
ERG1 plays an essential role in rat cardiomyocyte fate decision by mediating AKT signaling
Sign Up to like & getrecommendations! Published in 2021 at "STEM CELLS"
DOI: 10.1002/stem.3328
Abstract: ERG1, a potassium ion channel, is essential for cardiac action potential repolarization phase. However, the role of ERG1 for normal development of the heart is poorly understood. Using the rat embryonic stem cells (rESCs) model,… read more here.
Keywords: erg1 plays; essential role; plays essential; role ... See more keywords
Essential role of a conserved aspartate for the enzymatic activity of plasmanylethanolamine desaturase
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-022-04238-w
Abstract: Plasmalogens are an abundant class of glycerophospholipids in the mammalian body, with special occurrence in the brain and in immune cell membranes. Plasmanylethanolamine desaturase (PEDS1) is the final enzyme of plasmalogen biosynthesis, which introduces the… read more here.
Keywords: peds1; enzymatic activity; essential role; plasmanylethanolamine desaturase ... See more keywords
An essential role for Arabidopsis Trs33 in cell growth and organization in plant apical meristems
Sign Up to like & getrecommendations! Published in 2019 at "Plant Cell Reports"
DOI: 10.1007/s00299-019-02497-9
Abstract: Trafficking protein particle (TRAPP) complexes subunit gene AtTrs33 plays an important role in keeping apical meristematic activity and dominance in Arabidopsis. TRAPP complexes, composed of multimeric subunits, are guanine–nucleotide exchange factors for certain Rab GTPases… read more here.
Keywords: growth; essential role; role; apical meristematic ... See more keywords
The Essential Role of Epigenetic Modifications in Neurodegenerative Diseases with Dyskinesia.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and molecular neurobiology"
DOI: 10.1007/s10571-021-01133-z
Abstract: Epigenetics play an essential role in the occurrence and improvement of many diseases. Evidence shows that epigenetic modifications are crucial to the regulation of gene expression. DNA methylation is closely linked to embryonic development in… read more here.
Keywords: epigenetic modifications; modifications neurodegenerative; essential role; neurodegenerative diseases ... See more keywords
Essential role of the endocytic site-associated protein Ecm25 in stress-induced cell elongation
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109122
Abstract: SUMMARY How cells adopt a different morphology to cope with stress is not well understood. Here, we show that budding yeast Ecm25 associates with polarized endocytic sites and interacts with the polarity regulator Cdc42 and… read more here.
Keywords: stress; cell elongation; induced cell; essential role ... See more keywords
Essential role of mouse Dead end1 in the maintenance of spermatogonia.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.11.003
Abstract: Dead end is a vertebrate-specific RNA-binding protein implicated in germ cell development. We have previously shown that mouse Dead end1 (DND1) is expressed in male embryonic germ cells and directly interacts with NANOS2 to cooperatively… read more here.
Keywords: essential role; spermatogonia; dead end1; dnd1 ... See more keywords
Essential role of promoter Co on the MoS2 catalyst in selective hydrodesulfurization of FCC gasoline
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Fuel Chemistry and Technology"
DOI: 10.1016/s1872-5813(18)30019-7
Abstract: Abstract The essential role of Co on the MoS2 catalyst in selective hydrodesulfurization (HDS) of FCC gasoline was investigated with ammonium tetrathiomolybdate supported on alumina modified with various amount of Co sulfide. According to the… read more here.
Keywords: essential role; fcc gasoline; catalyst selective; mos2 catalyst ... See more keywords
Understanding the Essential Role of PbI 2 Films in a High-PerformanceLead Halide Perovskite Photodetector
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Physical Chemistry C"
DOI: 10.1021/acs.jpcc.0c04488
Abstract: Hybrid lead halide perovskites fabricated via solution processing have been regarded as a promising candidate for next-generation optoelectronic devices owing to their outstanding optoelectronic pr... read more here.
Keywords: understanding essential; essential role; role pbi; films high ... See more keywords
Egress and invasion machinery of malaria: an in-depth look into the structural and functional features of the flap dynamics of plasmepsin IX and X
Sign Up to like & getrecommendations! Published in 2018 at "RSC Advances"
DOI: 10.1039/c8ra04360d
Abstract: Plasmepsins, a family of aspartic proteases expressed by Plasmodium falciparum parasite, have been identified as key mediators in the onset of lethal malaria. Precedence has been placed on this family of enzymes due their essential… read more here.
Keywords: invasion machinery; essential role; family; flap dynamics ... See more keywords
Essential role for phytol kinase and tocopherol in tolerance to combined light and temperature stress in tomato
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erx356
Abstract: An essential role is identified for tocopherol in tomato under combined high-light and high-temperature stress. The dual antioxidant and membrane-stabilizing properties of tocopherol may explain its role in combined stress tolerance. read more here.
Keywords: tocopherol; temperature stress; role; essential role ... See more keywords