T‐type calcium channels as therapeutic targets in essential tremor and Parkinson's disease
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51735
Abstract: Neuronal action potential firing patterns are key components of healthy brain function. Importantly, restoring dysregulated neuronal firing patterns has the potential to be a promising strategy in the development of novel therapeutics for disorders of… read more here.
Keywords: tremor parkinson; essential tremor; parkinson disease;
Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21-Year Period.
Sign Up to like & getrecommendations! Published in 2025 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.70204
Abstract: Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts… read more here.
Keywords: tremor; year period; essential tremor; collective data ... See more keywords
Etiologic links between environmental and lifestyle factors and Essential tremor
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.758
Abstract: Essential tremor (ET) is one of the most common adult movement disorders, characterized by clinical tremor and other nonmotor symptoms. It is a progressive disease that shares features with other neurodegenerative diseases. ET is a… read more here.
Keywords: lifestyle factors; etiologic links; environmental lifestyle; links environmental ... See more keywords
Network Fingerprint of Stimulation‐Induced Speech Impairment in Essential Tremor
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Neurology"
DOI: 10.1002/ana.25958
Abstract: This study was undertaken to gain insights into structural networks associated with stimulation‐induced dysarthria (SID) and to predict stimulation‐induced worsening of intelligibility in essential tremor patients with bilateral thalamic deep brain stimulation (DBS). read more here.
Keywords: stimulation induced; stimulation; network fingerprint; fingerprint stimulation ... See more keywords
Probabilistic Mapping Reveals Optimal Stimulation Site in Essential Tremor
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26324
Abstract: The objective of this study was to obtain individual clinical and neuroimaging data of patients undergoing deep brain stimulation (DBS) for essential tremor (ET) from 5 different European centers to identify predictors of outcome and… read more here.
Keywords: essential tremor; stimulation; stimulation site; optimal stimulation ... See more keywords
Therapeutic Potential of Agmatine in Essential Tremor Through Regulation of Lingo‐1 and Inflammatory Pathways
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70241
Abstract: Essential tremor (ET) is a prevalent movement disorder, yet current therapeutic options remain limited. Emerging evidence implicates leucine‐rich repeat and immunoglobulin‐like domain‐containing protein (Lingo‐1) and neuroinflammation in the pathophysiology of ET. This study aimed to… read more here.
Keywords: tremor; therapeutic potential; agmatine essential; essential tremor ... See more keywords
Transcranial MRI‐guided high‐intensity focused ultrasound for treatment of essential tremor: A pilot study on the correlation between lesion size, lesion location, thermal dose, and clinical outcome
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25878
Abstract: Transcranial MR‐guided high‐intensity focused ultrasound (tcMRgFUS) is a promising noninvasive method to treat medication‐refractory essential tremor. read more here.
Keywords: focused ultrasound; intensity focused; high intensity; guided high ... See more keywords
Optimizing Botox regimens in patients with adductor spasmodic dysphonia and essential tremor of voice: A 31‐year experience
Sign Up to like & getrecommendations! Published in 2022 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.915
Abstract: The purpose of this study was to quantitatively compare the effectiveness of unilateral and bilateral botulinum toxin A (BTX‐A) injections for mitigating undesirable weak/breathy voice quality and dysphagia for patients with adductor spasmodic dysphonia and/or… read more here.
Keywords: dysphonia essential; patients adductor; spasmodic dysphonia; voice ... See more keywords
Essential Tremor and Depression
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DOI: 10.1002/mdc3.12530
Abstract: Depression and neuropsychiatric disorders in individuals with essential tremor (ET) are not well characterized in the literature. read more here.
Keywords: depression; tremor depression; essential tremor;
Does Added Objective Tremor Monitoring Improve Clinical Outcomes in Essential Tremor Treatment?
Sign Up to like & getrecommendations! Published in 2018 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.12554
Abstract: Essential tremor (ET) with an estimated prevalence of 2-3% of the US population can impair daily function and negatively impact patient quality of life1. Tremor can be rated by summary measures like the Global Clinical… read more here.
Keywords: essential tremor; objective tremor; added objective; monitoring improve ... See more keywords
Questionable Dystonia in Essential Tremor Plus: A Video‐Based Assessment of 19 Patients
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.12838
Abstract: In 2018, the consensus statement on the classification of tremor has included a new terminology “Essential Tremor Plus,” defined as tremor with the characteristics of essential tremor (ET) with additional soft neurological signs, including questionable… read more here.
Keywords: video; questionable dystonia; patients questionable; tremor ... See more keywords