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Published in 2022 at "Clinical Cardiology"
DOI: 10.1002/clc.23924
Abstract: The ability to opacify the left ventricle and delineate the endocardium after intravenous injection of microbubble ultrasound enhancing agents is of established value to quantify volumes and function in suboptimal unenhanced images, particularly in stress…
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Keywords:
established emerging;
contrast;
contrast agents;
enhancing agents ... See more keywords
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Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108445
Abstract: Liver fibrogenesis is defined as a dynamic and highly integrated process occurring during chronic injury to liver parenchyma that can result in excess deposition of extracellular matrix (ECM) components (i.e., liver fibrosis). Liver fibrogenesis, together…
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Keywords:
emerging basic;
established emerging;
update established;
fibrogenesis update ... See more keywords
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Published in 2020 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2020.154183
Abstract: Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease affecting approximately 25% of the global population. Although a majority of NAFLD patients will never experience liver-related symptoms it is estimated that…
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Keywords:
emerging factors;
established emerging;
fatty liver;
disease ... See more keywords
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Published in 2022 at "Immunological Reviews"
DOI: 10.1111/imr.13158
Abstract: Neutrophils are the most abundant innate immune cells in human blood, emerging as important players in a variety of diseases. Mitochondria are bioenergetic, biosynthetic, and signaling organelles critical for cell fate and function. Mitochondria have…
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Keywords:
function;
established emerging;
mitochondria neutrophils;
emerging roles ... See more keywords
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Published in 2019 at "Obesity Reviews"
DOI: 10.1111/obr.12770
Abstract: Tremendous progress has been made in the genetic elucidation of obesity over the past two decades, driven largely by technological, methodological and organizational innovations. Current strategies for identifying obesity‐predisposing loci/genes, including cytogenetics, linkage analysis, homozygosity…
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Keywords:
established emerging;
emerging strategies;
code obesity;
crack genetic ... See more keywords
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Published in 2023 at "Hypertension"
DOI: 10.1161/hypertensionaha.122.17947
Abstract: Cardiovascular disease and cancer are 2 of the leading causes of death worldwide. Although improvements in outcomes have been noted for both disease entities, the success of cancer therapies has come at the cost of…
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Keywords:
emerging cancer;
cancer;
established emerging;
hypertension ... See more keywords
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Published in 2020 at "NeoReviews"
DOI: 10.1542/neo.21-10-e699
Abstract: Inborn errors of metabolism (IEMs) are inherited defects in a metabolic pathway resulting in clinical disease. The overall goal of therapy is to restore metabolic homeostasis while minimizing the deleterious effects of the interruption. Conventional…
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Keywords:
established emerging;
errors metabolism;
treatments patients;
emerging treatments ... See more keywords
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Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16020320
Abstract: Fabry disease (FD) is a rare, X-linked inherited disorder of glycosphingolipid metabolism. It leads to the progressive accumulation of globotriaosylceramide within lysosomes due to a deficiency of α-galactosidase A enzyme. It involves multiple organs, predominantly…
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Keywords:
established emerging;
disease established;
treatment fabry;
treatment ... See more keywords
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Published in 2019 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics11050245
Abstract: Brain tumors are characterized by very high mortality and, despite the continuous research on new pharmacological interventions, little therapeutic progress has been made. One of the main obstacles to improve current treatments is represented by…
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Keywords:
blood brain;
established emerging;
blood;
brain barrier ... See more keywords