Establishment of in vitro culture system for Codonopsis pilosula transgenic hairy roots
Sign Up to like & getrecommendations! Published in 2020 at "3 Biotech"
DOI: 10.1007/s13205-020-2130-9
Abstract: The aim of the study was to establish a reliable system of transgenic hairy roots in Codonopsis pilosula through Agrobacterium-mediated genetic transformation. For this, we optimized several steps in the process of A. rhizogenes strain… read more here.
Keywords: system; hairy roots; transgenic hairy; codonopsis pilosula ... See more keywords
Establishment of an In Vitro-In Vivo Correlation for Melanin Binding and the Extension of the Ocular Half-Life of Small Molecule Drugs.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.9b00769
Abstract: A large variety of drugs bind effectively to melanin and this binding influences their ocular pharmacokinetic and distribution profiles. We aimed to establish a correlation between in vitro melanin binding and in vivo ocular pharmacokinetics… read more here.
Keywords: melanin; small molecule; correlation; drug ... See more keywords
Abstract A19: Establishment of in vitro and in vivo models of inflammatory myofibroblastic tumor
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.sarcomas17-a19
Abstract: Inflammatory myofibroblastic tumors (IMTs) are sarcomas of soft tissue that most commonly arise in children, adolescents, and young adults. If not cured by surgery, IMT has a high propensity for local recurrence as multifocal nodules,… read more here.
Keywords: tumor; alk driven; inflammatory myofibroblastic; vitro ... See more keywords