Tuning the efficacy of esterase-activatable prodrug nanoparticles for the treatment of colorectal malignancies.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.120705
Abstract: Colorectal cancer (CRC) is one of the most common and lethal human cancers, and the clinical outcomes remain unsatisfactory because of the lack of effective and safe therapeutic regimens. Here, we describe a practical and… read more here.
Keywords: sn38; efficacy; esterase activatable; esterase ... See more keywords
An esterase-activatable curcumin prodrug for tumor-targeting therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03952d
Abstract: A tumor-targeting therapy strategy is urgently needed to increase the accumulation of drugs in tumors and reduce the side effects in normal tissues. Herein, we developed an esterase-activatable curcumin prodrug Cur-RGD for tumor-targeting therapy. Armed… read more here.
Keywords: esterase activatable; activatable curcumin; tumor targeting; targeting therapy ... See more keywords