[Acquired C1 esterase inhibitor deficiency via bradykinin-mediated angioedema: Four cases].
Sign Up to like & getrecommendations! Published in 2018 at "Annales de dermatologie et de venereologie"
DOI: 10.1016/j.annder.2018.02.012
Abstract: BACKGROUND Acquired C1-esterase inhibitor (C1-INH) deficiency angioedema (C1-INH-AAE) is a form of bradykinin-mediated angioedema. This rare disorder is due to acquired consumption of C1-INH, hyperactivation of the classic pathway of human complement, and potentially fatal… read more here.
Keywords: inh aae; acquired esterase; esterase inhibitor; mediated angioedema ... See more keywords
Intestinal angioedema caused by an acquired C1 esterase inhibitor deficiency associated with underlying splenic marginal zone lymphoma
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DOI: 10.1080/08998280.2021.1885277
Abstract: Abstract A 75-year-old woman presented with recurrent abdominal pain and vomiting for 1 year and was later found to have splenomegaly and pancytopenia. This case report depicts a clinical picture of intestinal angioedema, a challenging… read more here.
Keywords: intestinal angioedema; acquired esterase; deficiency associated; esterase inhibitor ... See more keywords
Practical use of C1 esterase inhibitor concentrate for clinical amniotic fluid embolism
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DOI: 10.1111/jog.13717
Abstract: Amniotic fluid embolism (AFE) causes consumption coagulopathy, which requires a massive transfusion to save the mother's life. The preparation of such a massive transfusion is too time‐consuming in extremely emergent clinical settings and occasionally leads… read more here.
Keywords: transfusion; esterase inhibitor; fluid embolism; amniotic fluid ... See more keywords
Successful Long-Term Prophylactic Treatment With Subcutaneous C1 Esterase Inhibitor in a Patient With Hereditary Angioedema
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DOI: 10.1177/0897190019857407
Abstract: Background: Hereditary angioedema (HAE) patients suffer from recurrent swellings. Current standard therapy consists of C1 esterase inhibitor (C1-INH) and bradykinin receptor B2 antagonists. Severe courses require prophylactic treatment. For such patients, it has been demonstrated… read more here.
Keywords: inh; esterase inhibitor; treatment; hereditary angioedema ... See more keywords
Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice
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DOI: 10.1371/journal.pone.0186652
Abstract: C1 esterase inhibitor (C1-INH) can inhibit multiple pathways (complement, contact-kinin, coagulation, and fibrinolysis) that are all implicated in the pathophysiology of asthma. We explored the effect of human plasma-derived C1-INH on allergic lung inflammation in… read more here.
Keywords: plasma; allergic lung; esterase inhibitor; lung inflammation ... See more keywords
Patients With Severe Hereditary Angioedema Treated With Subcutaneous C1-Esterase Inhibitor (C1-INH [SC]) to Reduce the Incidence and Severity of Attacks: Results From a Phase 3 Trial
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DOI: 10.1542/peds.142.1_meetingabstract.812
Abstract: Background: Hereditary angioedema (HAE), caused by absolute or functional deficiency of C1-esterase inhibitor (C1-INH), is characterized by recurrent, disfiguring, and potentially life-threatening attacks of subcutaneous and submucosal edema. The mean age of first attack is… read more here.
Keywords: phase trial; hereditary angioedema; inhibitor inh; esterase inhibitor ... See more keywords
Managing Diagnosis, Treatment, and Burden of Disease in Hereditary Angioedema Patients with Normal C1-Esterase Inhibitor
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Asthma and Allergy"
DOI: 10.2147/jaa.s398333
Abstract: Abstract Hereditary angioedema (HAE) is a rare, chronic, and debilitating genetic disorder characterized by recurrent and unpredictable swelling episodes that primarily affect the subcutaneous and/or submucosal tissues of the extremities, larynx, face, abdomen, and genitals.… read more here.
Keywords: hae; hereditary angioedema; hae inh; diagnosis ... See more keywords