Engineering a bacterial platform for total biosynthesis of caffeic acid derived phenethyl esters and amides.
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2017.09.011
Abstract: Caffeic acid has been widely recognized as a versatile pharmacophore for synthesis of new chemical entities, among which caffeic acid derived phenethyl esters and amides are the most extensively-investigated bioactive compounds with potential therapeutical applications.… read more here.
Keywords: caffeic acid; acid derived; derived phenethyl; phenethyl esters ... See more keywords
Valorization of Lactate Esters and Amides into Value-Added Biobased (Meth)acrylic Polymers
Sign Up to like & getrecommendations! Published in 2024 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.4c00891
Abstract: (Meth)acrylic polymers are massively produced due to their inherently attractive properties. However, the vast majority of these polymers are derived from fossil resources, which is not aligned with the tendency to reduce gas emissions. In… read more here.
Keywords: meth acrylic; lactate esters; acrylic polymers; valorization lactate ... See more keywords
Nickel-Catalyzed Asymmetric Hydrogenation of γ-Keto Acids, Esters, and Amides to Chiral γ-Lactones and γ-Hydroxy Acid Derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00826
Abstract: A highly efficient asymmetric hydrogenation of a series of γ-keto acid derivatives, including γ-keto acids, esters, and amides, using a Ni-(R,R)-QuinoxP* complex as the catalyst has been developed to afford chiral γ-hydroxy acid derivatives with… read more here.
Keywords: esters amides; asymmetric hydrogenation; acids esters; keto ... See more keywords
Manganese-Catalyzed α-Alkylation of Ketones, Esters, and Amides Using Alcohols
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.8b03720
Abstract: Herein we report the manganese-catalyzed C–C bond-forming reactions via α-alkylation of ketones, amides, and esters, using primary alcohols. β-Alkylation of secondary alcohols by primary alcohols to obtain α-alkylated ketones is also reported. The reactions are… read more here.
Keywords: manganese catalyzed; catalyzed alkylation; esters amides; alkylation ... See more keywords
Catalytic enantioselective synthesis of α-aryl α-hydrazino esters and amides.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc02478c
Abstract: Catalysts generated by combinations of Pd(TFA)2 and pyridine-hydrazone ligands have allowed the asymmetric 1,2-addition of aryl boronic acids to N-carbamoyl (Cbz and Fmoc) protected glyoxylate-derived hydrazones, yielding α-aryl α-hydrazino esters/amides in high enantioselectivities. Subsequent removal… read more here.
Keywords: catalytic enantioselective; aryl hydrazino; hydrazino esters; esters amides ... See more keywords
Insights into self-degradation of cysteine esters and amides under physiological conditions yield new cleavable chemistry.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00684k
Abstract: An unprecedented H2S release from cysteine esters and amides (CysO/NHR) under physiological conditions was discovered and the plausible mechanism was proposed. Alkylation of the amino moiety of cysteine esters enables the H2S release to be… read more here.
Keywords: insights self; esters amides; chemistry; cysteine esters ... See more keywords
Yttrium-Catalyzed Regioselective Aminolysis of 2,3-Epoxy Esters and Amides
Sign Up to like & getrecommendations! Published in 2023 at "Synlett"
DOI: 10.1055/a-2077-5084
Abstract: Herein a yttrium-catalyzed regioselective ring opening reaction of 2,3-epoxy esters and amides with amines as nucleophiles is pre-sented. This method features high regiocontrol, enantiospecific SN2 reaction pathway, broad substrate scope and mild reaction condi-tions, furnishing… read more here.
Keywords: epoxy esters; catalyzed regioselective; yttrium catalyzed; esters amides ... See more keywords