Stereospecific Transformations of Alkylboronic Esters Enabled by Direct Boron-to-Zinc Transmetalation.
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DOI: 10.1021/jacs.3c01677
Abstract: Chiral secondary organoboronic esters, when activated with t-butyllithium, are shown to undergo efficient stereoretentive transmetalation with either zinc acetate or zinc chloride. This reaction provides chiral secondary alkylzinc reagents that are configurationally stable under practical… read more here.
Keywords: transformations alkylboronic; stereospecific transformations; zinc; transmetalation ... See more keywords