Noncatalytic destruction of 5-acylcomanic acid esters in the presence of 2-methylindoles as a new method for the synthesis of indolylchalcones
Sign Up to like & getrecommendations! Published in 2017 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-017-2147-0
Abstract: Ethyl esters of 5-acylcomanic acids reacted with 2-methylindoles in 3:1 propanol–water mixture in the absence of catalyst, resulting in pyrone ring opening and destruction of the molecular framework and leading to trans-indolylchalcones in 52–70% yields. read more here.
Keywords: noncatalytic destruction; destruction acylcomanic; acid esters; destruction ... See more keywords
Concise synthesis of oxacyclic compounds using highly discriminative two-way transformations of α,β-unsaturated esters in the presence of enones.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc03287k
Abstract: Highly discriminative transformation of α,β-unsaturated esters in the presence of enones using two types of phosphonium salts, and their application to the synthesis of oxacyclic compounds in six steps in one pot have been achieved. read more here.
Keywords: oxacyclic compounds; unsaturated esters; highly discriminative; synthesis oxacyclic ... See more keywords