Oxygen Atom Migration of Allylic Esters via an Organocatalyzed Claisen‐type Rearrangement
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202401401
Abstract: Direct transforming molecular skeleton to the other useful one is highly desirable for synthetic chemists. Oxygen atom migration of allylic esters is a powerful avenue for skeleton editing, and various methodologies involving palladium, Lewis acid… read more here.
Keywords: atom migration; oxygen atom; allylic esters; esters via ... See more keywords
Asymmetric Multi-Atom Insertion of Esters via Rh-Catalyzed Ring Opening of Oxabicyclic Alkenes.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c00971
Abstract: Precise skeletal manipulation involving insertion, deletion, and replacement has garnered considerable attention within the synthetic chemistry community. Among these processes, multi-atom insertion reactions in acyclic compounds remain a formidable challenge, primarily due to the low… read more here.
Keywords: multi atom; via catalyzed; asymmetric multi; insertion ... See more keywords
Enantioselective Synthesis of α-Allyl Amino Esters via Hydrogen-Bond Donor Catalysis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b05556
Abstract: We report a chiral-squaramide-catalyzed enantio- and diastereoselec-tive synthesis of α-allyl amino esters. The optimized protocol provides access to N-carbamoyl-protected amino esters via nucleophilic allyla-tion of readily accessible α-chloro glycinates. A variety of useful α-allyl amino… read more here.
Keywords: amino esters; esters via; allyl amino; synthesis allyl ... See more keywords
Cu(I)-Catalyzed stereoselective synthesis of trisubstituted Z-enol esters via interrupting the 1,3-O-transposition reaction
Sign Up to like & getrecommendations! Published in 2018 at "Organic chemistry frontiers"
DOI: 10.1039/c8qo00664d
Abstract: An efficient Cu(I)-catalyzed stereoselective synthesis of trisubstituted Z-enol esters via interrupting the 1,3-O-transposition process is reported. This method provided a convenient approach to highly functionalized Z-enol esters with mild reaction conditions and wide substrate scope. read more here.
Keywords: trisubstituted enol; esters via; stereoselective synthesis; catalyzed stereoselective ... See more keywords
Dynamic kinetic resolution of α-F-β-ketone amides (esters) via Ir/f-diaphos-catalyzed asymmetric hydrogenation
Sign Up to like & getrecommendations! Published in 2024 at "Organic Chemistry Frontiers"
DOI: 10.1039/d4qo00125g
Abstract: Highly reactive and highly stereoselective asymmetric hydrogenation of α-F-β-ketone amides (esters) via Ir/f-diaphos-catalyzed dynamic kinetic resolution is reported. read more here.
Keywords: via diaphos; diaphos catalyzed; amides esters; esters via ... See more keywords
Synthesis of α-Amino Esters via α-Nitro or α-Oxime Esters: A Review
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DOI: 10.1055/s-0036-1589506
Abstract: This review is an in-depth survey of the reported synthetic approaches for the preparation of racemic α-amino esters via the reduction of α-nitro or α-oxime ester intermediates. Accordingly, it describes the many pathways that have… read more here.
Keywords: oxime esters; amino esters; esters via; synthesis amino ... See more keywords
Isoniazid Linked to Sulfonate Esters via Hydrazone Functionality: Design, Synthesis, and Evaluation of Antitubercular Activity
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15101301
Abstract: Isoniazid (INH) is one of the key molecules employed in the treatment of tuberculosis (TB), the most deadly infectious disease worldwide. However, the efficacy of this cornerstone drug has seriously decreased due to emerging INH-resistant… read more here.
Keywords: sih1 sih13; sulfonate esters; esters via; inh ... See more keywords