In Vivo Estimates of Liver Metabolic Flux Assessed by 13C-Propionate and 13C-Lactate Are Impacted by Tracer Recycling and Equilibrium Assumptions.
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DOI: 10.1016/j.celrep.2020.107986
Abstract: Isotope-based assessment of metabolic flux is achieved through a judicious balance of measurements and assumptions. Recent publications debate the validity of key assumptions used to model stable isotope labeling of liver metabolism in vivo. Here, we… read more here.
Keywords: metabolic flux; estimates liver; lactate; propionate ... See more keywords