Estimating optimal dynamic treatment strategies under resource constraints using dynamic marginal structural models.
Sign Up to like & getrecommendations! Published in 2021 at "Statistics in medicine"
DOI: 10.1002/sim.9107
Abstract: Methods for estimating optimal treatment strategies typically assume unlimited access to resources. However, when a health system has resource constraints, such as limited funds, access to medication, or monitoring capabilities, medical decisions must account for… read more here.
Keywords: resource constraints; treatment; treatment strategies; estimating optimal ... See more keywords
Estimating the Optimal Number of Clusters Via Internal Validity Index
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DOI: 10.1007/s11063-021-10427-8
Abstract: Estimating the optimal number of clusters (NC) is pivotal in cluster analysis. From the viewpoint of sample geometry, a novel internal clustering validity index, which is termed the between-within cluster (BWC) index, is designed in… read more here.
Keywords: data sets; number clusters; index; optimal number ... See more keywords
Estimating the Optimal Number of Clusters k in a Dataset Using Data Depth
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DOI: 10.1007/s41019-019-0091-y
Abstract: This paper proposes a new method called depth difference (DeD), for estimating the optimal number of clusters (k) in a dataset based on data depth. The DeD method estimates the k parameter before actual clustering… read more here.
Keywords: optimal number; depth; number clusters; estimating optimal ... See more keywords
Estimating Individualized Treatment Regimes from Crossover Designs
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DOI: 10.1111/biom.13186
Abstract: The field of precision medicine aims to tailor treatment based on patient-specific factors in a reproducible way. To this end, estimating an optimal individualized treatment regime (ITR) that recommends treatment decisions based on patient characteristics… read more here.
Keywords: individualized treatment; medicine; treatment; estimating individualized ... See more keywords
Estimating the optimal individualized treatment rule from a cost-effectiveness perspective.
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DOI: 10.1111/biom.13406
Abstract: Optimal individualized treatment rules (ITRs) provide customized treatment recommendations based on subject characteristics to maximize clinical benefit in accordance with the objectives in precision medicine. As a result, there is growing interest in developing statistical… read more here.
Keywords: individualized treatment; optimal individualized; treatment; estimating optimal ... See more keywords
Estimating optimal individualized treatment rules with multistate processes.
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DOI: 10.1111/biom.13864
Abstract: Multistate process data are common in studies of chronic diseases such as cancer. These data are ideal for precision medicine purposes as they can be leveraged to improve more refined health outcomes, compared to standard… read more here.
Keywords: individualized treatment; methodology; estimating optimal; treatment rules ... See more keywords