LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "estradiol synthesis" as a keyword



NRDR inhibits estradiol synthesis and is associated with changes in reproductive traits in pigs

Sign Up to like & get
recommendations! Published in 2019 at "Molecular Reproduction and Development"

DOI: 10.1002/mrd.23080

Abstract: Cumulus cells secreting steroid hormones have important functions in oocyte development. Several members of the short‐chain dehydrogenase/reductase (SDR) family are critical to the biosynthesis of steroid hormones. NADPH‐dependent retinol dehydrogenase/reductase ( NRDR), a member of… read more here.

Keywords: estradiol synthesis; associated changes; reproductive traits; cumulus granulosa ... See more keywords

Local effect of bisphenol A on the estradiol synthesis of ovarian granulosa cells from PCOS

Sign Up to like & get
recommendations! Published in 2017 at "Gynecological Endocrinology"

DOI: 10.1080/09513590.2016.1184641

Abstract: Abstract Close relationship between polycystic ovary syndrome (PCOS) and bisphenol A (BPA) has drawn much attention in recent years, while the underlying mechanisms are poorly understood. In our study, we aim to detect BPA concentration… read more here.

Keywords: estradiol synthesis; granulosa cells; pcos patients;

High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis

Sign Up to like & get
recommendations! Published in 2024 at "Gut Microbes"

DOI: 10.1080/19490976.2024.2412381

Abstract: ABSTRACT High-fat diet (HFD) has been linked to female infertility. However, the specific age at which HFD impacts ovarian function and the underlying mechanisms remain poorly understood. Here, we administered a HFD to female mice… read more here.

Keywords: estradiol synthesis; oocyte quality; synthesis; hfd ... See more keywords

KAT2B regulates estradiol synthesis via H3K27ac/PPARα in granulosa cells of PCOS patients

Sign Up to like & get
recommendations! Published in 2025 at "Journal of Translational Medicine"

DOI: 10.1186/s12967-025-06848-x

Abstract: Polycystic ovary syndrome (PCOS) is one of the main cause of female infertility worldwide, however the aetiology of PCOS remains elusive. In our previous microarray analysis of granulosa cells (GCs), Lysine Acetyltransferase 2B (KAT2B) was… read more here.

Keywords: estradiol synthesis; pcos patients; pcos; expression ... See more keywords