Estradiol treatment improves biological rhythms in a preclinical rat model of menopause
Sign Up to like & getrecommendations! Published in 2019 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2019.08.029
Abstract: The perimenopausal transition at middle age is often associated with hot flashes and sleep disruptions, metabolic changes, and other symptoms. Whereas the mechanisms for these processes are incompletely understood, both aging (AG) and a loss… read more here.
Keywords: temperature; estradiol treatment; treatment; rhythms ... See more keywords
Previous estradiol treatment during midlife maintains transcriptional regulation of memory-related proteins by ERα in the hippocampus in a rat model of menopause
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2021.05.022
Abstract: Previous midlife estradiol treatment, like continuous treatment, improves memory and results in lasting increases in hippocampal levels of estrogen receptor (ER) α and ER-dependent transcription in ovariectomized rodents. We hypothesized that previous and continuous midlife… read more here.
Keywords: estradiol treatment; estradiol; midlife; previous estradiol ... See more keywords
17β-Estradiol Treatment Protects Lungs Against Brain Death Effects in Female Rat Donor.
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation"
DOI: 10.1097/tp.0000000000003467
Abstract: BACKGROUND Brain death (BD) affects the viability of lungs for transplantation. A correlation exists between high lung inflammation after BD and the decrease in female sex hormones, especially estradiol. Therefore, we investigated the effects of… read more here.
Keywords: estradiol treatment; lung; treatment; brain death ... See more keywords
Estradiol treatment in a large cohort of younger women with congenital hypogonadism: how much is enough?
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Endocrinology"
DOI: 10.1111/cen.14845
Abstract: 17beta-Estradiol (E2 ) is a critical contributor to women's bone-, cardiovascular-, sexual- and general health during normal reproductive life, and young women with hypogonadism (YWH) therefore require hormone replacement therapy (HRT) to mitigate symptoms, protect… read more here.
Keywords: hypogonadism; estradiol treatment; large cohort; younger women ... See more keywords