Estrogen-Functionalized Ru(II) Polypyridyl Complexes Self-Assemble into Aggregates and Exhibit Selective Phototoxicity against Breast Cancer Cells
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DOI: 10.1021/acs.inorgchem.5c03244
Abstract: Photodynamic therapy (PDT) constitutes a promising cancer treatment modality in which an administered photosensitizer is excited with visible light to induce the localized generation of cytotoxic reactive oxygen species (ROS) at the tumor site, thus… read more here.
Keywords: chemistry; cancer; cancer cells; estrogen functionalized ... See more keywords
Estrogen-functionalized liposomes grafted with glutathione-responsive sheddable chotooligosaccharides for the therapy of osteosarcoma
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DOI: 10.1080/10717544.2018.1458920
Abstract: Abstract An estrogen (ES)-functionalized cationic liposomal system was developed and exploited for targeted delivery to osteosarcoma. Natural biocompatible chotooligosaccharides (COS, MW2-5 KDa) were covalently tethered to the liposomal surface through a disulfate bond (-SS-) to confer… read more here.
Keywords: cos; estrogen; chol cos; cos dox ... See more keywords