Implications of estrogen and its receptors in colorectal carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5242
Abstract: Estrogens have been implicated in the pathogenesis of various cancer types, including colorectal carcinoma (CRC). Estrogen receptors such as ERα and ERβ activate intracellular signaling cascades followed by binding to estrogen, resulting in important changes… read more here.
Keywords: implications estrogen; estrogen; estrogen receptors; colorectal carcinoma ... See more keywords
Assessment of Metabolic Regulation by Estrogen Receptors.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1920-9_21
Abstract: Estrogens, predominantly 17β-estradiol (E2), are a class of steroid hormones critical for diverse functions in the body both during normal physiology and disease. Primary actions of E2 include reproduction and development of secondary sexual characteristics.… read more here.
Keywords: estrogen receptors; metabolic regulation; physiology; assessment metabolic ... See more keywords
Targeting estrogen receptors in colorectal cancer
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05414-6
Abstract: Hormones have become a useful therapeutic aspect of clinical endocrinology but how to use them to optimize the health benefits and avoid adverse effects is a major challenge. Estrogen is an indispensable hormone for proper… read more here.
Keywords: receptors colorectal; colorectal cancer; estrogen; estrogen receptors ... See more keywords
Estrogen receptors participate in carcinogenesis signaling pathways by directly regulating NOD-like receptors.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.02.085
Abstract: Increasing evidence indicates that the NOD-like receptors (NLRs) family may act as critical back-up defenses and provide synergistic responses when confronted with persistent danger. However, the precise regulatory mechanism of NLRs and the contribution of… read more here.
Keywords: directly regulating; estrogen receptors; nod like; receptors participate ... See more keywords
Neurotoxic effects of aluminum are associated with its interference with estrogen receptors signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2020.01.004
Abstract: Aluminum compounds have been observed in various brain regions, and their accumulation has been associated with many neurodegenerative disorders. Neurotoxic effects of aluminum are attributed to reactive oxygen species generation, induction of apoptosis and inflammatory… read more here.
Keywords: protein; reduction; estrogen; estrogen receptors ... See more keywords
Oviduct morphology and estrogen receptors ERα and ERβ expression in captive Chinchilla lanigera (Hystricomorpha: Chinchillidae).
Sign Up to like & getrecommendations! Published in 2019 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2018.03.023
Abstract: Chinchilla lanigera is a hystricomorph rodent from South America whose reproductive biology presents particular characteristics that distinguishes it from other Rodentia species, such as low reproductive rate, seasonal breeding pattern, and long estrous cycle. Nevertheless,… read more here.
Keywords: chinchilla lanigera; estrogen receptors; morphology; oviduct ... See more keywords
Behavioral responses to emotional challenges in female rats living in a seminatural environment: The role of estrogen receptors
Sign Up to like & getrecommendations! Published in 2018 at "Hormones and Behavior"
DOI: 10.1016/j.yhbeh.2018.10.013
Abstract: Abstract Estrogen receptors (ERs) are involved in sexual as well as non‐sexual behaviors. In the present study we assessed the effects of stimuli inducing positive or negative affect on sociosexual, exploratory and fear‐related behaviors of… read more here.
Keywords: agonist; female rats; estrogen receptors; sexual behaviors ... See more keywords
Estrogen receptors and the aging brain
Sign Up to like & getrecommendations! Published in 2021 at "Essays in Biochemistry"
DOI: 10.1042/ebc20200162
Abstract: Abstract The female sex hormone estrogen has been ascribed potent neuroprotective properties. It signals by binding and activating estrogen receptors that, depending on receptor subtype and upstream or downstream effectors, can mediate gene transcription and… read more here.
Keywords: aging brain; estrogen; estrogen receptors; receptors aging ... See more keywords
Estrogen Receptors alpha and beta in Ovarian Cancer: Expression Level and Prognosis
Sign Up to like & getrecommendations! Published in 2018 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s1607672918050058
Abstract: The quantitative immunofluorescence assay of serous ovarian cancer tissue for the expression of estrogen receptors (ERα and ERβ) revealed a higher expression level of ERβ in comparison with ERα in all surgical tumor samples investigated.… read more here.
Keywords: estrogen receptors; expression; expression level; ovarian cancer ... See more keywords
Expression of Ezrin and Estrogen Receptors During Cervical Carcinogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Reproductive Sciences"
DOI: 10.1177/1933719116667222
Abstract: Rationale: Development of cervical squamous carcinoma (CXCA) is accompanied by changes in estrogen receptors (ERs, ERα and ERβ) and ezrin expression; however, reports have been conflicting. Using histologically documented staging of cervical biopsies, we determined… read more here.
Keywords: estrogen receptors; cxca; expression; cervical carcinogenesis ... See more keywords
Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications
Sign Up to like & getrecommendations! Published in 2017 at "Reproductive Sciences"
DOI: 10.1177/1933719116678686
Abstract: Uterine fibroids are the most common gynecologic tumors with a significant medical and financial burden. Several genetic, hormonal, and biological factors have been shown to contribute to the development and growth of fibroid tumors. Of… read more here.
Keywords: receptors signaling; signaling fibroids; kinase; pathobiology ... See more keywords