Advances in targeting estrogen synthesis and receptors in patients with endometriosis
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2022.2152325
Abstract: ABSTRACT Introduction Endometriosis is an estrogen-dependent disease on the background of progesterone resistance. Increased estrogen production, low estrogen metabolization, and altered estrogen receptors (ERs) expression contribute to the hyperestrogenic milieu within endometriotic lesions. Since estrogens… read more here.
Keywords: estrogen; disease; synthesis receptors; advances targeting ... See more keywords
Estrogen synthesis in the stomach of Sprague-Dawley rats: comparison to Wistar rats.
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DOI: 10.1538/expanim.20-0089
Abstract: Aromatase, an estrogen synthase, exists in the gastric parietal cells of Wistar rats. The stomach synthesizes large amounts of estrogens and secretes them into the portal vein. We have been particularly studying gastric estrogen synthesis… read more here.
Keywords: stomach sprague; estrogen synthesis; wistar rats; synthesis stomach ... See more keywords
MicroRNA-7a2 Contributes to Estrogen Synthesis and Is Modulated by FSH via the JNK Signaling Pathway in Ovarian Granulosa Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158565
Abstract: MicroRNA-7a2 (miR-7a2) plays fundamental roles in the female reproductive axis, and estrogen is indispensable for maintaining ovary function. However, the interaction between miR-7a2 and ovarian function is unclear. The present study aimed to determine whether… read more here.
Keywords: mir 7a2; signaling pathway; estrogen synthesis; synthesis ... See more keywords