Estrogenic potency of MC-LR is induced via stimulating steroidogenesis: In vitro and in vivo evidence.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental pollution"
DOI: 10.1016/j.envpol.2018.04.140
Abstract: Waterborne microcystin-LR (MC-LR) has been reported to disrupt sex hormones, while its estrogenic potency remains controversial. We hypothesized that MC-LR could induce estrogenic effects via disrupting sex hormone synthesis, and verified this hypothesis by in vitro… read more here.
Keywords: vitro vivo; estrogenic potency; steroidogenesis;
A critical assessment of the estrogenic potency of benzyl salicylate
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology Reports"
DOI: 10.1016/j.toxrep.2021.05.001
Abstract: Highlights • Benzyl salicylate (BS) is on priority lists for evaluation of estrogenic effects.• New data in both MCF7 (E-screen) and luciferase transactivation assays.• Potency of BS is 21′000′000-fold lower than estradiol in transactivation assay.•… read more here.
Keywords: benzyl salicylate; potency; estrogenic potency; potency benzyl ... See more keywords
Estrogenic potency of endocrine disrupting chemicals and their mixtures detected in environmental waters and wastewaters.
Sign Up to like & getrecommendations! Published in 2023 at "Chemosphere"
DOI: 10.2139/ssrn.4361195
Abstract: Endocrine disrupting chemicals such as natural and synthetic steroid hormones and bisphenols are among the most important pollutants in the aquatic environment. We performed an environmental chemical analysis of five Slovenian water samples, two rivers,… read more here.
Keywords: estrogenic potency; water; disrupting chemicals; endocrine ... See more keywords
Microbial Metabolism of the Soy Isoflavones Daidzein and Genistein in Postmenopausal Women: Human Intervention Study Reveals New Metabotypes
Sign Up to like & getrecommendations! Published in 2023 at "Nutrients"
DOI: 10.3390/nu15102352
Abstract: Background: Soy isoflavones belong to the group of phytoestrogens and are associated with beneficial health effects but are also discussed to have adverse effects. Isoflavones are intensively metabolized by the gut microbiota leading to metabolites… read more here.
Keywords: metabolism; daidzein genistein; soy; postmenopausal women ... See more keywords