Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner
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DOI: 10.1371/journal.ppat.1006344
Abstract: Autophagy is a eukaryotic catabolic process also participating in cell-autonomous defence. Infected host cells generate double-membrane autophagosomes that mature in autolysosomes to engulf, kill and digest cytoplasmic pathogens. However, several bacteria subvert autophagy and benefit… read more here.
Keywords: mycobacterium marinum; esx dependent; autophagic flux; autophagic response ... See more keywords