Renin–angiotensin system blockade alone or combined with ETA receptor blockade: effects on the course of chronic kidney disease in 5/6 nephrectomized Ren-2 transgenic hypertensive rats
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2016.1235184
Abstract: ABSTRACT Background: Early addition of endothelin (ET) type A (ETA) receptor blockade to complex renin–angiotensin system (RAS) blockade has previously been shown to provide better renoprotection against progression of chronic kidney disease (CKD) in Ren-2… read more here.
Keywords: blockade alone; receptor blockade; blockade; receptor ... See more keywords
Upregulation of the endothelin A (ETA) receptor and its association with neurodegeneration in a rodent model of glaucoma
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DOI: 10.1186/s12868-017-0346-3
Abstract: BackgroundPrimary open angle glaucoma is a heterogeneous group of optic neuropathies that results in optic nerve degeneration and a loss of retinal ganglion cells (RGCs) ultimately causing blindness if allowed to progress. Elevation of intraocular… read more here.
Keywords: layer; endothelin eta; elevation; receptor ... See more keywords
Role of Endothelin-1 Receptors in Limiting Leg Blood Flow and Glucose Uptake during Hyperinsulinemia in Type 2 Diabetes.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac008
Abstract: Skeletal muscle insulin resistance is a hallmark of individuals with type 2 diabetes mellitus (T2D). In healthy individuals insulin stimulates vasodilation, which is markedly blunted in T2D; however, the mechanism(s) remain incompletely understood. Investigations in… read more here.
Keywords: leg; eta receptor; type diabetes; glucose uptake ... See more keywords